عبادی گل تپه خ. ن.، شادی ا. 1398. ترکیبات زیست فعال ثانویه میکروارگانیسمهای دریایی و کاربرد آنها. فصلنامه علوم و فناوری دریا، 24(93): 70-56.
Abeliovich A., Shilo M. 1972. Photooxidative reactions of c-phycocyanin. Biochimica et Biophysica Acta (BBA) - Bioenergetics 283(3), 483-491.
Acker J.P., McGann L.E. 2003. Protective effect of intracellular ice during freezing? Cryobiology 46(2), 197-202.
Akaberi S., Krust D., Müller G., Frey W., Gusbeth, C. 2020. Impact of incubation conditions on protein and C-Phycocyanin recovery from Arthrospira platensis post- pulsed electric field treatment. Bioresource Technology 306, 123099.
Amaro H.M., Guedes A.C., Malcata F.X. 2011. Antimicrobial activities of microalgae: an invited review. Science against Microbial Pathogens: Communicating Current Research and Technological Advances 3, 1272-1284.
Antelo F.S., Anschau A., Costa J.A., Kalil S.J. 2010. Extraction and purification of C-phycocyanin from Spirulina platensis in conventional and integrated aqueous two-phase systems. Journal of the Brazilian Chemical Society 21(5), 921-926.
Batista A.P., Raymundo A., Sousa I., Empis J. 2006. Rheological characterization of coloured oil-in-water food emulsions with lutein and phycocyanin added to the oil and aqueous phases. Food Hydrocolloids 20(1), 44-52.
Benedetti S., Rinalducci S., Benvenuti F., Francogli S., Pagliarani S., Giorgi L., Micheloni M., D’Amici G. M., Zolla L., Canestrari F. 2006. Purification and characterization of phycocyanin from the blue-green alga Aphanizomenon flos-aquae. Journal of Chromatography B 833(1), 12-18.
Borowitzka M.A. 1995. Microalgae as sources of pharmaceuticals and other biologically active compounds. Journal of Applied Phycology 7(1), 3-15.
Chaiklahan R., Chirasuwan N., Bunnag B. 2012. Stability of phycocyanin extracted from Spirulina sp.: Influence of temperature, pH and preservatives. Process Biochemistry 47(4), 659-664.
Chaiklahan R., Chirasuwan N., Loha V., Tia S., Bunnag B. 2011. Separation and purification of phycocyanin from Spirulina sp. using a membrane process. Bioresource Technology 102(14), 7159-7164.
Chapman D.J., Cole W.J., Siegelman H.W. 1968. Phylogenetic implications of phycocyanobilin and C‐phycocyanin. American Journal of Botany 55(3), 314-316.
Chattopadhyay P.K., Gaylord B., Palmer A., Jiang N., Raven M.A., Lewis G., Reuter M.A., Nur-ur Rahman A.K.M., Price D.A., Betts M.R., Roederer M. 2012. Brilliant violet fluorophores: a new class of ultrabright fluorescent compounds for immunofluorescence experiments. Cytometry Part A 81(6), 456-466.
Chittapun S., Jonjaroen V., Khumrangsee K., Charoenrat T. 2020. C-phycocyanin extraction from two freshwater cyanobacteria by freeze thaw and pulsed electric field techniques to improve extraction efficiency and purity. Algal Research 46, 101789.
Cisneros M., Rito-Palomares M. 2004. A simplified strategy for the release and primary recovery of c-phycocyanin produced by Spirulina maxima. Chemical Biochimestry Eng Q 18(4), 385-90.
Cisneros M., Rito-Palomares M. 2004. A Simplified Strategy for the Release and Primary Recovery of c-phycocyanin Produced by Spirulina maxima. Chemical and Biochemical Engineering Quarterly 18(4), 385-390.
de Carvalho J.C., Magalhães A.I., de Melo Pereira G.V., Medeiros A.B.P., Sydney E.B., Rodrigues C., Aulestia D.T.M., de Souza Vandenberghe L.P., Soccol V.T., Soccol C.R. 2020. Microalgal biomass pretreatment for integrated processing into biofuels, Food, and Feed. Bioresource Technology 300, 122719.
Estrada J.P., Bescós P.B., Del Fresno A.V.J. 2001. Antioxidant activity of different fractions of Spirulina platensis protean extract. Il Farmaco 56(5-7), 497-500.
Fernández-Rojas B., Hernández-Juárez J., Pedraza-Chaverri J. 2014. Nutraceutical properties of phycocyanin. Journal of Functional Foods 11, 275-392.
Ferraro G., Imbimbo P., Marseglia A., Lucignano R., Monti D.M., Merlino, A. 2020. X-ray structure of C-phycocyanin from Galdieria phlegrea : Determinants of thermostability and comparison with a C-phycocyanin in the entire phycobilisome. Biochimica et Biophysica Acta (BBA)-Bioenergetics 1861(9), 148236.
Ferreira-Santos P., Nunes R., de Biasio F., Spigno G., Gorgoglione D., Teixeira J.A., Rocha C.M.R. 2020. Influence of thermal and electrical effects of ohmic heating on C-phycocyanin properties and biocompounds recovery from Spirulina platensis. LWT 128, 109491.
Galland-Irmouli A.V., Pons L., Luçon M., Villaume C., Mrabet N.T., Guéant J.L., Fleurence J. 2000. One-step purification of R-phycoerythrin from the red macroalga Palmaria palmata using preparative polyacrylamide gel electrophoresis. Journal of Chromatography B:Biomedical Sciences and Applications 739(1), 117-123.
Gantar M., Simović D., Djilas S., Gonzalez W.W., Miksovska J. 2012. Isolation, characterization and antioxidative activity of C-phycocyanin from Limnothrix sp. strain 37-2-1. Journal of Biotechnology 159(1-2), 21-26.
Garcia E.S., Lo, C., Eppink M.H., Wijffels R.H., Van den Berg C. 2019. Understanding mild cell disintegration of microalgae in bead mills for the release of biomolecules. Chemical Engineering Science 203, 380-390.
Glazer A.N. 1984. Phycobilisome a macromolecular complex optimized for light energy transfer. Biochimica et Biophysica Acta (BBA) - Reviews on Bioenergetics 768(1), 29-51.
Glazer A.N., Stryer L.U.B.E.R.T. 1983. Fluorescent tandem phycobiliprotein conjugates. Emission wavelength shifting by energy transfer. Biophysical Journal 43(3), 383-386.
Günerken E., D’Hondt E., Eppink M.H.M., Garcia-Gonzalez L., Elst K., Wijffels R.H. 2015. Cell disruption for microalgae biorefineries. Biotechnology Advances 33(2), 243-260.
Hadiyanto H., Harjanto G. D., Huzain M. L., Aji R. W. 2019, October. Production of antioxidant C-phycocyanin using extraction process of Spirulina platensis in large scale industry. In IOP conference series: Materials Science and Engineering Vol. 633, No. 1. IOP Publishing. p. 012025.
Hsieh-Lo M., Castillo G., Ochoa-Becerra M.A., Mojica L. 2019. Phycocyanin and phycoerythrin: Strategies to improve production yield and chemical stability. Algal Research 42, 101600.
Huang H.W., Hsu C.-P., Yang B.B., Wang C.-Y. 2013. Advances in the extraction of natural ingredients by high pressure extraction technology. Trends in Food Science & Technology 33(1), 54-62.
Ibañez E., Herrero M., Mendiola J. A., Castro-Puyana M. 2012. Extraction and characterization of bioactive compounds with health benefits from marine resources: macro and micro algae, cyanobacteria, and invertebrates. in marine bioactive compounds. Boston, MA: Springer US. pp. 55-98.
İlter I., Akyıl S., Demirel Z., Koç M., Conk-Dalay M., Kaymak-Ertekin F. 2018. Optimization of phycocyanin extraction from Spirulina platensis using different techniques. Journal of Food Composition and Analysis 70, 78-88.
Jaeschke D.P., Mercali G. D., Marczak L.D.F., Müller G., Frey W., Gusbeth C. 2019. Extraction of valuable compounds from Arthrospira platensis using pulsed electric field treatment. Bioresource Technology 283, 207-212.
Jaeschke D.P., Teixeira I.R., Marczak L.D.F., Mercali G.D. 2021. Phycocyanin from Spirulina: A review of extraction methods and stability. Food Research International 143, 110314.
Jespersen L., Strømdahl L.D., Olsen K., Skibsted L.H. 2005. Heat and light stability of three natural blue colorants for use in confectionery and beverages. European Food Research and Technology 220(3), 261-266.
Jian-Feng N.I.U., Guang-Ce W.A.N. G., Lin X.Z., Zhou B.C. 2007. Large-scale recovery of C-phycocyanin from Spirulina platensis using expanded bed adsorption chromatography. Journal of Chromatography B 850(1-2), 267-276.
Käferböck A., Smetana S., de Vos R., Schwarz C., Toepfl S., Parniakov O. 2020. Sustainable extraction of valuable components from Spirulina assisted by pulsed electric fields technology. Algal Research 48, 101914.
Kim S.-K., Ravichandran Y.D., Khan S.B., Kim Y.T. 2008. Prospective of the cosmeceuticals derived from marine organisms. Biotechnology and Bioprocess Engineering 13(5), 511-523.
Koubaa M., Imatoukene N., Drévillon L., Vorobiev E. 2020. Current insights in yeast cell disruption technologies for oil recovery: A review. Chemical Engineering and Processing - Process Intensification 150, 107868.
Kuddus M., Singh P., Thomas G., Al-Hazimi A. 2013. Recent developments in production and biotechnological applications of c-phycocyanin. BioMed Research International 2013.
Kumari R.P., Anbarasu K. 2014. Protective Role of C-Phycocyanin Against Secondary Changes During Sodium Selenite Mediated Cataractogenesis. Natural Products and Bioprospecting 4(2), 81-89.
Larrosa A.P.Q., Camara Á. S., Moura J.M., Pinto L. A. A. 2018. Spirulina sp. biomass dried/disrupted by different methods and their application in biofilms production. Food Science and Biotechnology 27(6), 1659-1665.
Li Y., Zhang Z., Paciulli M., Abbaspourrad A. 2020. Extraction of phycocyanin-A natural blue colorant from dried spirulina biomass: Influence of processing parameters and extraction techniques. Journal of Food Science 85(3), 727-735.
Martínez J.M., Luengo E., Saldaña G., Álvarez I., Raso J. 2017. C-phycocyanin extraction assisted by pulsed electric field from Artrosphira platensis. Food Research International 99, 1042-1047.
Montalescot V., Rinaldi T., Touchard R., Jubeau S., Frappart M., Jaouen P., Bourseau P., Marchal L. 2015. Optimization of bead milling parameters for the cell disruption of microalgae: Process modeling and application to Porphyridium cruentum and Nannochloropsis oculata. Bioresource Technology 196, 339-346.
Moon M., Mishra S.K., Kim C.W., Suh W. I., Park M.S., Yang J.-W. 2014. Isolation and characterization of thermostable phycocyanin from Galdieria sulphuraria. Korean Journal of Chemical Engineering 31(3), 490-495.
Moraes C.C., Sala L., Cerveira G.P., Kalil S. J. 2011. C-phycocyanin extraction from Spirulina platensis wet biomass. Brazilian Journal of Chemical Engineering 28(1), 45-49.
Muller P. 1994. Glossary of terms used in physical organic chemistry (IUPAC Recommendations 1994). Pure and Applied Chemistry 66(5), 1077-1184.
Ojha K.S., Aznar R., O’Donnell C., Tiwari B.K. 2020. Ultrasound technology for the extraction of biologically active molecules from plant, animal and marine sources. TrAC Trends in Analytical Chemistry 122, 115663.
Oliveira E.G., Rosa G.S., Moraes M.A., Pinto L.A.A. 2009. Characterization of thin layer drying of Spirulina platensis utilizing perpendicular air flow. Bioresource Technology 100(3), 1297-1303.
Ores J. da C., Amarante M.C.A. de Kalil, S. J. 2016. Co-production of carbonic anhydrase and phycobiliproteins by Spirulina sp. and Synechococcus nidulans. Bioresource Technology 219, 219-271.
Pan-utai W., Iamtham S. 2019. Extraction, purification and antioxidant activity of phycobiliprotein from Arthrospira platensis. Process Biochemistry 82, 189-198.
Patel A., Mishra S., Pawar R., Ghosh P.K. 2005. Purification and characterization of C-Phycocyanin from cyanobacterial species of marine and freshwater habitat. Protein Expression and Purification 40(2). 248-255.
Patil G., Chethana S., Madhusudhan M.C., Raghavarao K.S.M. S. 2008. Fractionation and purification of the phycobiliproteins from Spirulina platensis. Bioresource Technology 99(15), 7393-7396.
Patil G., Raghavarao K.S.M.S. 2007. Queous two phase extraction for purification of C-phycocyanin. Biochemical Engineering Journal 34(2), 156-164.
Pott R.W. 2019. The release of the blue biological pigment C-phycocyanin through calcium-aided cytolysis of live Spirulina sp. Coloration Technology 135(1), 17-21.
Ramos A., Acién F.G., Fernández-Sevilla J.M., González C.V., Bermejo R. 2010. Large-scale isolation and purification of C-phycocyanin from the cyanobacteria Anabaena marina using expanded bed adsorption chromatography. Journal of Chemical Technology & Biotechnology 85(6), 783-792.
Roquebert M.F., Bury E. 1993. Effect of freezing and thawing on cell membranes of Lentinus edodes, the shiitake mushroom. World Journal of Microbiology & Biotechnology 9(6), 641-647.
Samsonoff W., MacColl R. 2001. Biliproteins and phycobilisomes from cyanobacteria and red algae at the extremes of habitat. Archives of Microbiology 176(6), 400-405.
Sarada R., Pillai M.G., Ravishankar G.A. 1999. Phycocyanin from Spirulina sp: influence of processing of biomass on phycocyanin yield, analysis of efficacy of extraction methods and stability studies on phycocyanin. Process Biochemistry 34(8), 795-801.
Saran S., Puri N., Jasuja N. D., Kumar M., Sharma G. 2016. Optimization purification and characterization of Phycocyanin from Spirulina platensis. International Journal of Applied and Pure Science and Agriculture 2(3), 15-21.
Sekar S., Chandramohan M. 2008. Phycobiliproteins as a commodity: trends in applied research, patents and commercialization. Journal of Applied Phycology 20(2), 113-136.
Shanab S.M., Mostafa S.S., Shalaby E.A., Mahmoud G.I. 2012. Aqueous extracts of microalgae exhibit antioxidant and anticancer activities. Asian Pacific Journal of Tropical Biomedicine 2(8), 608-615.
Silveira S.T., Burkert J. D. M., Costa J.A.V., Burkert C.A.V., Kalil S. J. 2007. Optimization of phycocyanin extraction from Spirulina platensis using factorial design. Bioresource Technology 98(8), 1629-1634.
Silveira S.T., de Menezes Quines L.K., Burkert C.A.V., Kalil S.J. 2008. Separation of phycocyanin from Spirulina platensis using ion exchange chromatography. Bioprocess and Biosystems Engineering 31(5), 447-482.
Sloth J.K., Wiebe M.G., Eriksen N.T. 2006. Accumulation of phycocyanin in heterotrophic and mixotrophic cultures of the acidophilic red alga Galdieria sulphuraria. Enzyme and Microbial Technology 38(1-2), 168-175.
Sørensen L., Hantke A., Eriksen N.T. 2013. Purification of the photosynthetic pigment C-phycocyanin from heterotrophic Galdieria sulphuraria. Journal of the Science of Food and Agriculture 93(12), 2933–2938.
Sousa I., Gouveia L., Batista A. P., Raymundo A., Bandarra N. M. 2008. Microalgae in novel food products. Food Chemistry Research Developments 75-112.
Stanek M., Grubmayr K. 1998. Protonated 2,3-Dihydrobilindiones-Models for the Chromophores of Phycocyanin and the Red-Absorbing Form of Phytochrome. Chemistry - A European Journal 4(9), 1653-1659.
Su C.H., Liu C.S., Yang P.C., Syu K.S., Chiuh C.C. 2014. Solid–liquid extraction of phycocyanin from Spirulina platensis: Kinetic modeling of influential factors. Separation and Purification Technology 123, 64-68.
Su H.N., Wang Q.M., Li C.Y., Li K., Luo W., Chen B., Zhang X.-Y., Qin Q.L., Zhou B.C., Chen X.L., Zhang Y.Z., Xie B.B. 2017. Structural insights into the cold adaptation of the photosynthetic pigment-protein C-phycocyanin from an Arctic cyanobacterium. Biochimica et Biophysica Acta (BBA)- Bioenergetics 1858(4), 325-335.
Sun L, Wang S., Gong X., Chen L. 2004. A rod-linker-contained R-phycoerythrin complex from the intact phycobilisome of the marine red alga Polysiphonia urceolata. Journal of Photochemistry and Photobiology B: Biology 76(1-3), 1-11.
Sun L., Wang S., Zhao M., Fu, X., Gong X., Chen M., Wang L. 2009. Phycobilisomes from cyanobacteria. Handbook on Cyanobacteria: Biochemistry, Biotechnology and Application. New York: Nova Science Publishers 105-160.
Tavanandi H.A., Mittal R., Chandrasekhar J., Raghavarao K.S.M.S. 2018. Simple and efficient method for extraction of C-Phycocyanin from dry biomass of Arthospira platensis. Algal Research 31, 239-251.
Tavanandi H.A., Raghavarao K.S.M. S. 2020. Ultrasound-assisted enzymatic extraction of natural food colorant C-Phycocyanin from dry biomass of Arthrospira platensis. LWT 118, 108802.
Thangam R., Suresh V., Asenath Princy W., Rajkumar M., SenthilKumar N., Gunasekaran P., Rengasamy R., Anbazhagan C., Kaveri K., Kannan S. 2013. C-Phycocyanin from Oscillatoria tenuis exhibited an antioxidant and in vitro antiproliferative activity through induction of apoptosis and G0/G1 cell cycle arrest. Food Chemistry 140(1-2), 262–272.
Tiwari B.K. 2015. Ultrasound: A clean, green extraction technology. TrAC Trends in Analytical Chemistry 71, 100-109.
Vali Aftari R., Rezaei K., Mortazavi A., Bandani A. R. 2015. The Optimized Concentration and Purity of Spirulina platensis C-Phycocyanin: A Comparative Study on Microwave-Assisted and Ultrasound-Assisted Extraction Methods. Journal of Food Processing and Preservation 39(6), 3080-3091.
Vinatoru M., Mason T.J., Calinescu I. 2017. Ultrasonically assisted extraction (UAE) and microwave assisted extraction (MAE) of functional compound from plant materials. TrAC Trends in Analytical Chemistry 97, 159-178.
Vorobiev E., Lebovka N. 2009. Pulsed-electric-fields-induced effects in plant tissues: fundamental aspects and perspectives of applications. In Electrotechnologies for extraction from food plants and biomaterials. Springer, New York, NY. pp. 39-81.
Vorobiev E., Lebovka N. 2016. Extraction from foods and biomaterials enhanced by pulsed electric energy. In Innovative Food Processing Technologies. Woodhead Publishing. pp. 31-56.
Wang L., Qu Y., Fu X., Zhao M., Wang S., Sun L. 2014. Isolation, purification and properties of an R-phycocyanin from the phycobilisomes of a marine red macroalga Polysiphonia urceolata. PloS one 9(2), e87833.
Wenjun S., Cuijuan Z., Suying W. 2013. A Large-Scale Preparation Method of High Purity C-Phycocyanin. International Journal of Bioscience, Biochemistry and Bioinformatics,3(4), 293-297.
Yoshida A., Takagaki Y., Nishimune T. 1996. Enzyme Immunoassay for Phycocyanin as the Main Component of Spirulina Color in Foods. Bioscience, Biotechnology, and Biochemistry 60(1), 57-60.
Zhang Z., Cho S., Dadmohammadi Y., Li Y., Abbaspourrad A. 2021. Improvement of the storage stability of C-phycocyanin in beverages by high-pressure processing. Food Hydrocolloids 110, 106055.
Zinkoné T. R., Gifuni I., Lavenant L., Pruvost J., Marchal L. 2018. Bead milling disruption kinetics of microalgae: Process modeling, optimization and application to biomolecules recovery from Chlorella sorokiniana. Bioresource Technology 267, 458-465.
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